2020-2021年度科研成果
发表科研论文 | ||||
题目 | 作者 | 期刊 | 发表时间 | 级别 |
Neuropeptide Y mediates cardiac hypertrophy through microRNA-216b/FoxO4 signaling pathway | Jinghao Wang , Dan Hao, Lingfeng Zeng , Qianhui Zhang , Wei Huang# | International Journal of Medical Sciences | 2021.01 | SCI |
MicroRNA-369 attenuates hypoxia-induced cardiomyocyte apoptosis and inflammation via targeting TRPV3 | Jinghao Wang , Xu Chen , Wei Huang# | Brazilian Journal of Medical and Biological Research | 2021.01 | SCI |
Role of Tumor-Derived Extracellular Vesicles in Glioblastoma | Yunping Chen* , Yan Jin, Nan Wu | Cells | 2021.02 | SCI |
Inhibition of lncRNA Gm15834 attenuates autophagy-mediated myocardial hypertrophy via miR-30b-3p/ULK1 axis in mice | Chao Song* , Hanping Qi* , Yongsheng Liu , Yunping Chen , Pilong Shi , Shu Zhang , Jing Ren , Lixin Wang , Yonggang Cao , Hongli Sun | Mol Ther . | 2021.03 | SCI |
Shear stress inhibits cardiac microvascular endothelial cells apoptosis to protect against myocardial ischemia reperfusion injury via YAP/miR-206/PDCD4 signaling pathway | Qianlong Zhang* , Yonggang Cao , Yongsheng Liu , Wei Huang , Jing Ren , Peng Wang, Chao Song , Kai Fan , Lina Ba , Lixin Wang, Hongli Sun | Biochemical Pharmacology | 2021.04 | SCI |
Overexpression of PELP1 in Lung Adenocarcinoma Promoted E-2 Induced Proliferation, Migration and Invasion of the Tumor Cells and Predicted a Worse | Dongmei Zhang* , Jiali Dai , Yu Pan , Xiuli Wang , Juanjuan Qiao , Hironobu Sasano , Baoshan Zhao , Keely M McNamara , Xue Guan , Lili Liu , Yanzhi Zhang , Monica S M Chan , Shuwen Cao , Ming Liu, Sihang Song , Lin Wang# | Pathol Oncol Res . | 2021.04 | SCI |
A novel Danshensu/tetramethylpyrazine protects against Myocardial Ischemia Reperfusion Injury in rats | Jinghao Wang , Kai Fan , Cong He , Qingyang Wang , Qianhui Zhang, Wei Huang# | Int J Med Sci . | 2021.05 | SCI |
LncRNA Miat knockdown alleviates endothelial cell injury through regulation of miR-214-3p/Caspase-1 signalling during atherogenesis | Tao Li , Peiyang Tu , Jianbo Bi , Yanling Sun , Dejun Yu , Jinghao Wang , Baoshan Zhao# | Clin Exp Pharmacol Physiol . | 2021.08 | SCI |
Nano-Drug Design Based on the Physiological Properties of Glulathione | Wenhua Li , Minghui Li , Jing Qi # | Molecules | 2021.09 | SCI |
Neutrophil-like cell membrane-coated siRNA of lncRNA AABR07017145.1 therapy for cardiac hypertrophy via inhibiting ferroptosis of cardiac microvascular endothelial cells by regulating the MMP9/TIMP1 balance | Pilong Shi*, Minghui Li , Chao Song , Hanping Qi , Lina Ba , Yonggang Cao , Meitian Zhang , Yawen Xie , Jing Ren , Jiabi Wu , Ping Ren , Hongli Sun | Mol Ther Nucleic Acids
| 2021.10 | SCI |
Resveratrol on the Metabolic Reprogramming in Liver: Implications for Advanced Atherosclerosis | Ying Ma* , Dongliang Li , Wenfeng Liu , Xiaoxiao Liu , Yingqi Xu , Xinrui Zhong , Fengnan Zhi , Xueling Jia , Yanan Jiang , Yuhua Fan# | Front Pharmacol | 2021.10 | SCI |
The Egr-1/miR-15a-5p/GPX4 axis regulates ferroptosis in acute myocardial infarction | Kai Fan*, Wei Huang , Hanping Qi , Chao Song , Cong He , Yongsheng Liu , Qianlong Zhang , Lixin Wang , Hongli Sun | Eur J Pharmacol
| 2021.10 | SCI |
注*为第一作者；#为通讯作者。
科研立项 | |||||
课题编号 | 立项名称 | 主持人 | 项目来源 | 执行年限 | 资助金额（万元） |
H3502 | 转录因子Nkx2-5经核心转录调控环路靶向超级增强子驱动的lncRNA Snhg7介导铁死亡参与心肌肥厚的作用及机制 | 孙宏丽 | 国家自然科学基金项目（面上项目） | 2022.01.01-2025.12.31 | 55 |
C1130 | circRNA-myh8通过招募核心转录因子Oct4协同超级增强子激活UTF1转录在肺血管重构中的作用 | 邢妍 | 国家自然科学基金项目（面上项目） | 2022.01.01-2025.12.31 | 58 |
H0213 | FOXK1抑制线粒体自噬基因PINK1转录活性增加动脉张力促进高血压的机制研究 | 张彦秋 | 国家自然科学基金项目（青年科学基金项目） | 2022.01.01-2025.12.31 | 24 |
JQ2021H001 | 低频电刺激抑制巨噬细胞焦亡稳定动脉粥样硬化易损斑块的分子机制 | 杨力明 | 黑龙江省自然科学基金项目(杰出青年项目) | 2021.07.01-2024.07.01 | 50 |
ZD2021H002 | circ-calm4介导肺动脉平滑肌铁死亡的作用和机制 | 于航 | 黑龙江省自然科学基金项目(重点项目) | 2021.07.01-2024.07.01 | 50 |
LH2021H024 | 剪切力感受器Notch1与心肌肥厚心脏微血管障碍的关系及机制 | 巴立娜 | 黑龙江省自然科学基金项目(联合引导) | 2021.07.01-2024.07.01 | 10 |
LH2021H019 | circRNAmyh8协同超级增强子促进肺血管重构的分子机制 | 邢妍 | 黑龙江省自然科学基金项目(联合引导) | 2021.07.01-2024.07.01 | 10 |
CXZX-ZXKT0 | SPM全脑康复训练 | 王鹏 | 创新中心支持项目 | 2021.06.01-20246-06.01 | 4 |
CXZX-ZXKT05 | 抗过敏中药化妆品研发转化项目 | 曹永刚 | 创新中心支持项目 | 2021.06.01-20246-06.01 | 4 |
JFYQPY202101 | 超级增强子驱动的Frrs1调控铁自噬介导铁死亡通路参与心肌肥厚作用及机制研究 | 宋超 | 教师发展基金(优青培育基金) | 2021.08.01-2024.08.01 | 10 |
JFMSPY202101 | circ-calm4介导肺动脉平滑肌铁死亡的作用和机制 | 于航 | 教师发展基金(国自然培育项目) | 2021.08.01-2024.08.01 | 10 |
2021年度，基础医学院共发表SCI文章12篇，单篇最高影响因子11.454。共获国家自然科学基金3项，其中面上项目2项，青年科学基金项目1项。黑龙江省自然科学基金资助4项，其中，黑龙江省自然科学基金杰出青年项目1项，黑龙江省自然科学基金重点项目1项，黑龙江省自然科学基金联合引导项目2项。其他各类资助项目4项。累计科研经费285万元。
